Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains.



The mechanistic insight of a specific interaction between 15d-Prostaglandin-J2 and eIF4A suggests an evolutionary conserved role across species.

Comparative lipidomic profiling of the human commensal bacterium Propionibacterium acnes and its extracellular vesicles.

Head formation requires Dishevelled degradation that is mediated by March2 in concert with Dapper1.



Overexpression of MicA induces production of OmpC-enriched outer membrane vesicles that protect against Salmonella challenge.

Helicobacter pylori-derived extracellular vesicles increased in the gastric juices of gastric adenocarcinoma patients and induced inflammation mainly via specific targeting of gastric epithelial cells.

Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels.

Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling.

Proteomic analysis of extracellular vesicles derived from Propionibacterium acnes.

Tbx2 regulates anterior neural specification by repressing FGF signaling pathway.



Emerging roles of lipids in Wnt signaling during development.

Interactions between Transmembrane Helices within Monomers of the Aquaporin AtPIP2;1 Play a Crucial Role in Tetramer Formation.

PLD1 regulates xenopus convergent extension movements by mediating Frizzled7 endocytosis for Wnt/PCP signal activation.



Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling.

Inhibition of CYP4A reduces hepatic endoplasmic reticulum stress and features of diabetes in Mice.

Meteorin regulates mesendoderm development by enhancing nodal expression.



Role of Sp5 as an essential early regulator of neural crest specification in Xenopus.

Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling.

β-Arrestin 1 mediates non-canonical Wnt pathway to regulate convergent extension movements.

BMP signal attenuates FGF pathway in anteroposterior neural patterning.

Selective fluorescent detection of RNA in living cells by using imidazolium-based cyclophane.



Dual functions of DP1 promote and stabilize biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning.

Analysis of the expression of microtubule plus-end tracking proteins.

Wnt/planar cell polarity signaling in the regulation of convergent extension movements during Xenopus gastrulation.

Dab2 is pivotal for endothelial cell migration by mediating VEGF expression in cancer cells.

Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation.



Rab3d is required for Xenopus anterior neurulation by regulating Noggin secretion.

Negative regulation of activin signal transduction.

The involvement of Eph-Ephrin signaling in tissue separation and convergence during Xenopus gastrulation movements.

Role of Tbx2 in defining the territory of pronephric nephron.



XPteg (Xenopus Proximal Tubules-Expressed Gene) Is essential for pronephric mesoderm specification and tubulogenesis.



Negative feedback regulation of Wnt signaling by Gbg-mediated reduction of Dishevelled.

Identification of a novel negative regulator of activin/nodal signaling in mesendodermal formation of Xenopus embryos.

Xenopus Wntless and the Retromer complex cooperate to regulate XWnt4 secretion.

Multiple isoforms of β-TrCP display differential activities in the regulation of Wnt signaling.



Direct inhibition of GSK3β by the phosphorylated cytoplasmic domain of LRP6 in Wnt/β-Catenin signaling.

Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus convergent extension movements.

Regulation of Activin/Nodal Signaling by Rap2-directed receptor trafficking.



Identification and expression of XRTN1-A and XRTN1-C in Xenopus laevis.

Xenopus cDNA microarray identification of genes with endodermal organ expression.

Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements.

Negative regulation of Activin/Nodal Signaling by SRF during Xenopus gastrulation.



Xenopus Dab2 is required for embryonic angiogenesis.

Neuralized2 regulates a Notch ligand in cooperation with Mind bomb-1.

Role of PKA as a negative regulator of PCP signaling pathway during Xenopus gastrulation movements.

Novel function of POSH, a JNK scaffold, as an E3 ubiquitin ligase for the Hrs stability on early endosomes.



The assembly of POSH-JNK regulates Xenopus anterior neural development.

Isolation and comparison of Xenopus FGF-8b with FGF-8a.

Rap2 is required for Wnt/beta-catenin signaling pathway in Xenopus early development.

JNK and ROKa function in the noncanonical Wnt/RhoA signaling pathway to regulate Xenopus convergent extension movements.

XEpac, a guanine nucleotide-exchange factor for Rap GTPase, is a novel hatching gland specific marker during the Xenopus embryogenesis.

Identification and expression of XRTN2 and XRTN3 during Xenopus development.



A novel TBP-interacting zinc finger protein functions in early development of Xenopus laevis.

A putative xenopus Rho-GTPase activating proien(Xr GAP) gene is expressed in the notochord and brain during the early embryogenesis.

Local activation of protein kinase A inhibits gastrulation movements in Xenopus laevis.



Cloning and expression of a novel amadillo motif containing gene in Xenopus.

Bone morphogenic protein-4-induced activation of Xretpos is mediated by Smads and Olf-1/EBF associated zinc finger (OAZ).

Hydrogen peroxide-induced current in Xenopus oocyte: its similar current characteristics induced by removal of extracellular calcium.

Xenopus Cdc42 regulates convergent extension movements during gastrulation through Wnt/Ca2+ signaling pathway.



A novel Xenopus acetyltransferase with a dynamic expression in early development.

Poly(A) binding protein II in xenopus laevis is expressed in developing brain and pancreas.



Differential stereoselectivity of D- and L-myo-inositol 1,2,4,5-tetrakisphosphate binding to the inositol 1,4,5-trisphosphate receptor and 3-kinase.

A novel family of retrotransposons in Xenopus with a developmentally regulated expression.

Identification and developmental expression of par-6 gene in Xenopus laevis.

A novel gene family with a developmentally regulated expression in Xenopus laevis.

Modulation of lysophosphatidic acid-induced Cl- currents by protein kinases A and C in the Xenopus oocyte.



The involvement of cAMP signaling pathway in axis specification in Xenopus embryos.



Identification and expression study of a Xenopus homologue of prenylated SNARE gene.

Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes : functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes.

Inhibition of the adenylyl cyclase and activation of the phosphatidylinositol pathway in oocytes through expression of serotonin receptors does not induce oocyte maturation.



Expression of the fibroblast growth factor-2 gene during chick development.

Insulin-induced maturation of Xenopus oocytes is inhibited by microinjection of a Brassica napus cDNA clone with high similarity to a mammalian receptor for activated protein kinase C.



Molecular Cloning of Chicken Embryo Fibroblast Growth Factor 1 cDNA and Its Expression during Early Embryogenesis.

Reducing PIP2 hydrolysis, Ins(1,4,5)P3 receptor availability, or calcium gradients inhibitsprogesterone-stimulated Xenopus oocyte maturation.

Oscillation of inositol polyphosphates in the embryonic cleavage cycle of the Xenopus laevis.



Embryonic expression of Fgf-6 is restricted to the skeletal muscle lineage.



Reducing inositol lipid hydrolysis, Ins(1,4,5)P3 receptor availability, or Ca2+ gradients lengthens the duration of the cell cycle in Xenopus laevis blastomeres.



The effects of inositol trisphosphates and inositol tetrakisphosphate on Ca2+ release and Cl- current pattern in the Xenopus laevis oocyte.



Inositol 1,4,5-trisphosphate-induced calcium release in the organelle layers of the stratified, intact egg of Xenopus laevis.